Active Homocystrol®+ TMG is a food supplement formulated with riboflavin (B2), pyridoxine (B6), methylated folic acid in its active form Quatrefolic®, methylcobalamin (B12), betaine, and choline: Betaine contributes to normal homocysteine metabolism. Choline, folates, and vitamins B6 and B12 contribute to normal homocysteine metabolism. Directions for use: Take 2 capsules daily.